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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNMA1
All Species:
18.18
Human Site:
T461
Identified Species:
40
UniProt:
Q12791
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12791
NP_001154824.1
1236
137560
T461
A
L
F
K
R
H
F
T
Q
V
E
F
Y
Q
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
O18867
1151
128915
H417
N
V
E
I
V
F
L
H
N
I
S
P
N
L
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08460
1209
134378
T461
A
L
F
K
R
H
F
T
Q
V
E
F
Y
Q
G
Rat
Rattus norvegicus
Q62976
1209
134356
T462
A
L
F
K
R
H
F
T
Q
V
E
F
Y
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510131
822
92544
L90
L
H
N
I
S
P
N
L
E
L
E
A
L
F
K
Chicken
Gallus gallus
Q8AYS8
1137
127628
I405
E
I
V
F
L
H
N
I
S
P
N
L
E
L
E
Frog
Xenopus laevis
Q90ZC7
1196
134483
T429
A
L
F
K
K
H
F
T
Q
V
E
F
Y
Q
G
Zebra Danio
Brachydanio rerio
NP_001139072
1184
133307
P427
Y
Q
G
S
V
L
N
P
H
D
L
A
R
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03720
1200
133083
A440
A
D
A
C
L
V
L
A
N
K
Y
C
Q
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95V25
1140
129511
H408
D
V
E
V
V
F
L
H
R
V
V
P
D
L
E
Sea Urchin
Strong. purpuratus
XP_783726
1307
143907
T487
A
L
F
K
R
H
F
T
Q
L
Q
Y
F
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93
N.A.
N.A.
94
93.9
N.A.
62.1
87.8
84
84.3
N.A.
54.8
N.A.
51.2
49
Protein Similarity:
100
N.A.
93.1
N.A.
N.A.
94.3
94.1
N.A.
63.7
89.5
88.1
88.3
N.A.
68.5
N.A.
64.8
63.5
P-Site Identity:
100
N.A.
0
N.A.
N.A.
100
100
N.A.
6.6
6.6
93.3
0
N.A.
6.6
N.A.
6.6
73.3
P-Site Similarity:
100
N.A.
13.3
N.A.
N.A.
100
100
N.A.
20
13.3
100
0
N.A.
6.6
N.A.
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
0
10
0
0
0
0
10
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
10
0
0
10
10
0
% D
% Glu:
10
0
19
0
0
0
0
0
10
0
46
0
10
0
28
% E
% Phe:
0
0
46
10
0
19
46
0
0
0
0
37
10
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
46
% G
% His:
0
10
0
0
0
55
0
19
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
19
0
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
46
10
0
0
0
0
10
0
0
0
0
19
% K
% Leu:
10
46
0
0
19
10
28
10
0
19
10
10
10
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
28
0
19
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
10
0
10
0
10
0
19
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
46
0
10
0
10
46
0
% Q
% Arg:
0
0
0
0
37
0
0
0
10
0
0
0
10
0
0
% R
% Ser:
0
0
0
10
10
0
0
0
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
0
% T
% Val:
0
19
10
10
28
10
0
0
0
46
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
10
10
37
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _